Concerning the antibody titer (Ab's) against the most common infectious diseases in broiler production, the present findings prove that using aqueous nanosuspension 1.5% one time every one or two weeks, and 1% one time every week improve significantly Ab's against ND, IB, and IBD, respectively, compared with those provided with tap-water either with or without antibiotics. The improvement in Ab's against ND, IB, and IBD diseases ascribed to aqueous nanosuspension. We believe that this finding is referred to nanoflakes of clay minerals that were added to the drinking water of chickens. This is because nanotechnology has the potential to change the particles of material from large scale to nanoscale generally 1–300 nm in size . At this small size, the properties and characteristics can differ considerably compared to those at large scales . Unfortunately, there is a lack or null information about the use of nanotechnology in poultry production particularly broiler feeding. However, we believe that the chemical composition of aqueous nanosuspension that contains mineral elements plays a role in improving antibodies production noticed in the present study. In this regard, it has been reported that minerals are one of the most widely supplements used in poultry and animal nutrition . Additionally, the way in which minerals are found influences their bioavailability, and so far, if they have low bioavailability, the animal will not make suitable use of them. Recently,  cited that nanoparticles have a surface area much larger than microparticles, which may improve the bioavailability of the minerals used in this study. In this regard, Ref.  pointed out four possible application of nanotechnology in animal production of which is the administration of probiotics, medicines, and nutrient. In more recent study, Ref.  designed and evaluated in vitro, sodium selenite nanoparticles for oral use in ruminants using copolymers of metacrylate, sensible to pH, such that they would not be degraded in the rumen (near neutral pH), but would in the abomasums, whose pH is acid due to the secretion of HCl. On the other hand, silver nanoparticles were tested unsuccessfully (with antibacterial aims) in chicken embryos . Antibody is immunoglobulin produced by B-cell that is used by the immune system to identify and neutralize foreign objects such as bacteria and viruses . Furthermore, one of the common functions of antibody titer is to see if the immune system is creating antibodies to a person's or animal's own body. It has been previously reported that through a number of mechanism, dietary components can have direct and indirect implications on the intensity and efficacy of immune response. Some nutrients are capable of increasing immune response such as Zn and Se, while others are capable of decreasing immune response. Researches have clearly established that nutritional deficiencies, as well as certain excesses, impair the birds' ability to amount an effective immune response. Based on the results, reported herein, and reports in the literature, we believe that the improvement in antibodies titer against ND, IB, and IBD diseases might be due to the increase of bioavailability of nanoflakes of clay minerals added to drinking water of chickens, which may enhance immune system functions. Regarding this, Ref.  developed a highly available nanoparticles of ferric phosphate, proving that at a nanoscale, this source can increase its nutritional value. This article presents an overview of the use of nanotechnology in poultry industry particularly broiler feeding, and discusses “nanotech” in using new nanomaterials in poultry nutrition. Additionally, in the not-so-distant future chickens and human may live better lives due to intelligent chickens' feed.