The ocular response analyzer (ORA) is a new indentation tonometer that subjects the cornea to an increasing then decreasing air pulse, and uses the corresponding two applanation pressures and to estimate the intraocular pressure (IOP). The present study aims to improve the accuracy of IOP estimation through representative numerical simulation of the ORA procedure. A parametric study has been carried out to consider the effect of corneal thickness, curvature, age, and true IOP on the and measurements. Based on the obtained database of input and output parameters, an equation has been suggested relating the and measurements to the value of IOP. The equation is intended to make IOP estimates independent of corneal stiffness, which varies with size and age. The equation has been tested against a clinical data set obtained at Moorfields Eye Hospital involving 144 subjects, and found to produce IOP estimates that are less dependent on corneal size and age than published equations.
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e-mail: d.alhasso@dundee.ac.uk
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August 2009
Research Papers
Assessment of the Ocular Response Analyzer as a Tool for Intraocular Pressure Measurement
Daad Alhasso,
Daad Alhasso
Division of Civil Engineering,
e-mail: d.alhasso@dundee.ac.uk
University of Dundee
, Dundee DD1 4HN, UK
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Aachal Kotecha,
Aachal Kotecha
NIHR Biomedical Research Centre for Ophthalmology,
Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology
, London EC1V 9EL, UK; Department of Optometry and Visual Science, City University
, London EC1V 0HB, UK
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David Garway-Heath
David Garway-Heath
NIHR Biomedical Research Centre for Ophthalmology,
Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology
, London EC1V 9EL, UK; GB Bietti Foundation for Research in Ophthalmology—IRCCS
, Rome, Italy
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Daad Alhasso
Division of Civil Engineering,
University of Dundee
, Dundee DD1 4HN, UKe-mail: d.alhasso@dundee.ac.uk
Aachal Kotecha
NIHR Biomedical Research Centre for Ophthalmology,
Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology
, London EC1V 9EL, UK; Department of Optometry and Visual Science, City University
, London EC1V 0HB, UK
David Garway-Heath
NIHR Biomedical Research Centre for Ophthalmology,
Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology
, London EC1V 9EL, UK; GB Bietti Foundation for Research in Ophthalmology—IRCCS
, Rome, ItalyJ Biomech Eng. Aug 2009, 131(8): 081010 (9 pages)
Published Online: July 6, 2009
Article history
Received:
August 8, 2008
Revised:
November 11, 2008
Published:
July 6, 2009
Citation
Elsheikh, A., Alhasso, D., Kotecha, A., and Garway-Heath, D. (July 6, 2009). "Assessment of the Ocular Response Analyzer as a Tool for Intraocular Pressure Measurement." ASME. J Biomech Eng. August 2009; 131(8): 081010. https://doi.org/10.1115/1.3148462
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