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Journal Articles

Simulated Effects of Acute Left Ventricular Myocardial Infarction on Mitral Regurgitation in an Ovine Model

Hao Liu, Michael S. Sacks, Natalie T. Simonian, Joseph H. Gorman, III, Robert C. Gorman
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2024, 146(10): 101009.
Paper No: BIO-23-1153
https://doi.org/10.1115/1.4065376
Published Online: June 6, 2024
View Article titled, Simulated Effects of Acute Left Ventricular Myocardial Infarction on Mitral Regurgitation in an Ovine Model
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Topics: Valves, Simulation, Deformation, Geometry, Myocardium
Journal Articles

A New Strain Energy Function Representing the Passive Behavior of the Myocardium

Tawfik M. Hussein, John C. Criscione
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2023, 145(11): 111004.
Paper No: BIO-22-1149
https://doi.org/10.1115/1.4062778
Published Online: August 8, 2023
View Article titled, A New Strain Energy Function Representing the Passive Behavior of the Myocardium
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Topics: Deformation, Myocardium, Slabs, Stiffness, Stress, Testing, Uncertainty, Errors, Fibers, Goodness-of-fit tests
Journal Articles

Paired Pressure–Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts

Rachel C. Childers, Aaron J. Trask, Jun Liu, Pamela A. Lucchesi, Keith J. Gooch
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2021, 143(8): 081003.
Paper No: BIO-20-1275
https://doi.org/10.1115/1.4050541
Published Online: April 21, 2021
View Article titled, Paired Pressure–Volume Loop Analysis and Biaxial Mechanical Testing Characterize Differences in Left Ventricular Tissue Stiffness of Volume Overload and Angiotensin-Induced Pressure Overload Hearts
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Topics: Biological tissues, Mechanical testing, Pressure, Stiffness, Testing, Mechanical properties, Myocardium
Includes: Supplementary data
Journal Articles

Longitudinal Reinforcement of Acute Myocardial Infarcts Improves Function by Transmurally Redistributing Stretch and Stress

Ana Cristina Estrada, Kyoko Yoshida, Samantha A. Clarke, Jeffrey W. Holmes
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2020, 142(2): 021009.
Paper No: BIO-18-1444
https://doi.org/10.1115/1.4044030
Published Online: October 11, 2019
View Article titled, Longitudinal Reinforcement of Acute Myocardial Infarcts Improves Function by Transmurally Redistributing Stretch and Stress
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Topics: Fibers, Finite element model, Myocardium, Pressure, Stress, Materials properties
Journal Articles

Cardiac Protective Engineering

Shu Q. Liu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. September 2019, 141(9): 090801.
Paper No: BIO-19-1058
https://doi.org/10.1115/1.4043434
Published Online: August 2, 2019
View Article titled, Cardiac Protective Engineering
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Topics: Proteins, Wounds, Biological tissues, Myocardium, Liver
Journal Articles

The Impact of Hemodynamic Reflex Compensation Following Myocardial Infarction on Subsequent Ventricular Remodeling

Colleen M. Witzenburg, Jeffrey W. Holmes
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2019, 141(9): 091010.
Paper No: BIO-19-1091
https://doi.org/10.1115/1.4043867
Published Online: August 2, 2019
View Article titled, The Impact of Hemodynamic Reflex Compensation Following Myocardial Infarction on Subsequent Ventricular Remodeling
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Topics: Hemodynamics, Pressure, Myocardium, Blood
Journal Articles

Relative Contributions of Matrix and Myocytes to Biaxial Mechanics of the Right Ventricle in Pulmonary Arterial Hypertension

Daniela Vélez-Rendón, Erica R. Pursell, Justin Shieh, Daniela Valdez-Jasso
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2019, 141(9): 091011.
Paper No: BIO-19-1111
https://doi.org/10.1115/1.4044225
Published Online: August 2, 2019
View Article titled, Relative Contributions of Matrix and Myocytes to Biaxial Mechanics of the Right Ventricle in Pulmonary Arterial Hypertension
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Topics: Anisotropy, Biological tissues, Mechanical properties, Mechanical testing, Myocardium, Outflow, Stress, Hemodynamics, Modeling, Stiffness
Journal Articles

Differential Effects of Isoproterenol on Regional Myocardial Mechanics in Rat Using Three-Dimensional Cine DENSE Cardiovascular Magnetic Resonance

Xiaoyan Zhang, Zhan-Qiu Liu, Dara Singh, David K. Powell, Charles S. Chung, Kenneth S. Campbell, Jonathan F. Wenk
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2019, 141(6): 060904.
Paper No: BIO-18-1025
https://doi.org/10.1115/1.4041042
Published Online: April 22, 2019
View Article titled, Differential Effects of Isoproterenol on Regional Myocardial Mechanics in Rat Using Three-Dimensional Cine DENSE Cardiovascular Magnetic Resonance
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Topics: Cardiovascular system, Magnetic resonance, Torsion, Shear (Mechanics), Myocardium, Diseases
Journal Articles

Comparison of Biomechanical Properties and Microstructure of Trabeculae Carneae, Papillary Muscles, and Myocardium in the Human Heart

Fatemeh Fatemifar, Marc D. Feldman, Meagan Oglesby, Hai-Chao Han
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2019, 141(2): 021007.
Paper No: BIO-18-1239
https://doi.org/10.1115/1.4041966
Published Online: December 5, 2018
View Article titled, Comparison of Biomechanical Properties and Microstructure of Trabeculae Carneae, Papillary Muscles, and Myocardium in the Human Heart
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Topics: Muscle, Myocardium, Stress, Biological tissues
Journal Articles

Compressibility and Anisotropy of the Ventricular Myocardium: Experimental Analysis and Microstructural Modeling

Eoin McEvoy, Gerhard A. Holzapfel, Patrick McGarry
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2018, 140(8): 081004.
Paper No: BIO-17-1590
https://doi.org/10.1115/1.4039947
Published Online: May 24, 2018
View Article titled, Compressibility and Anisotropy of the Ventricular Myocardium: Experimental Analysis and Microstructural Modeling
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Topics: Anisotropy, Biological tissues, Compressibility, Compression, Fibers, Modeling, Myocardium, Stress, Shear (Mechanics), Simulation
Journal Articles

2015 Richard Skalak Award

Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Editorial
J Biomech Eng. February 2016, 138(2): 020203.
Paper No: BIO-15-1582
https://doi.org/10.1115/1.4032217
Published Online: January 27, 2016
View Article titled, 2015 Richard Skalak Award
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Topics: Bearings, Bioengineering, Biomechanical engineering, Biomechanics, Biomedical engineering, Computer simulation, Engineering disciplines, Finite element model, Geometry, Leadership
Journal Articles

Numerical Evaluation of Myofiber Orientation and Transmural Contractile Strength on Left Ventricular Function

Xiaoyan Zhang, Premi Haynes, Kenneth S. Campbell, Jonathan F. Wenk
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. April 2015, 137(4): 044502.
Paper No: BIO-14-1291
https://doi.org/10.1115/1.4028990
Published Online: April 1, 2015
View Article titled, Numerical Evaluation of Myofiber Orientation and Transmural Contractile Strength on Left Ventricular Function
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Topics: Biomechanics, Boundary-value problems, Fibers, Finite element model, Myocardium, Physiology, Pumps, Simulation, Stress, Tension
Journal Articles

Bioengineered Stromal Cell-Derived Factor-1α Analogue Delivered as an Angiogenic Therapy Significantly Restores Viscoelastic Material Properties of Infarcted Cardiac Muscle

Alen Trubelja, John W. MacArthur, Joseph J. Sarver, Jeffrey E. Cohen, George Hung, Yasuhiro Shudo, Alexander S. Fairman, Jay Patel, Bryan B. Edwards, Scott M. Damrauer, William Hiesinger, Pavan Atluri, Y. Joseph Woo
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. August 2014, 136(8): 084501.
Paper No: BIO-13-1583
https://doi.org/10.1115/1.4027731
Published Online: June 2, 2014
View Article titled, Bioengineered Stromal Cell-Derived Factor-1α Analogue Delivered as an Angiogenic Therapy Significantly Restores Viscoelastic Material Properties of Infarcted Cardiac Muscle
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Topics: Biological tissues, Myocardium, Patient treatment, Stress, Testing, Viscoelastic materials, Viscoelasticity, Relaxation (Physics)
Journal Articles

Biomechanics of Cardiac Electromechanical Coupling and Mechanoelectric Feedback

Emily R. Pfeiffer, Jared R. Tangney, Jeffrey H. Omens, Andrew D. McCulloch
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021007.
Paper No: BIO-13-1409
https://doi.org/10.1115/1.4026221
Published Online: February 5, 2014
View Article titled, Biomechanics of Cardiac Electromechanical Coupling and Mechanoelectric Feedback
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Topics: Arrhythmias, Biological tissues, Feedback, Muscle, Excitation, Heat conduction, Membranes, Myocardium, Electrophysiology, Currents
Journal Articles

Impact of Weightlessness on Cardiac Shape and Left Ventricular Stress/Strain Distributions

Ilana Iskovitz, Mohammad Kassemi, James D. Thomas
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2013, 135(12): 121008.
Paper No: BIO-13-1053
https://doi.org/10.1115/1.4025464
Published Online: October 24, 2013
View Article titled, Impact of Weightlessness on Cardiac Shape and Left Ventricular Stress/Strain Distributions
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Topics: Geometry, Gravity (Force), Pressure, Shapes, Stress, Weightlessness, Deformation, Fibers, Finite element analysis, Myocardium
Journal Articles

The Role of Cardiac Fibroblasts in Extracellular Matrix-Mediated Signaling During Normal and Pathological Cardiac Development

Kelly Elizabeth Sullivan, Lauren Deems Black, III
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2013, 135(7): 071001.
Paper No: BIO-12-1618
https://doi.org/10.1115/1.4024349
Published Online: June 11, 2013
View Article titled, The Role of Cardiac Fibroblasts in Extracellular Matrix-Mediated Signaling During Normal and Pathological Cardiac Development
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Topics: Diseases, Fibroblasts, Myocardium, Physiology, Proteins, Stiffness, Stress, Biological tissues, Pressure, Signals
Journal Articles

Effects of Myocardial Infarction on the Distribution and Transport of Nutrients and Oxygen in Porcine Myocardium

Bryce H. Davis, Yoshihisa Morimoto, Chris Sample, Kevin Olbrich, Holly A. Leddy, Farshid Guilak, Doris A. Taylor
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. October 2012, 134(10): 101005.
https://doi.org/10.1115/1.4007455
Published Online: October 1, 2012
View Article titled, Effects of Myocardial Infarction on the Distribution and Transport of Nutrients and Oxygen in Porcine Myocardium
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Topics: Diffusion (Physics), Glucose, Myocardium, Oxygen, Biological tissues, Patient treatment
Journal Articles

Viscoelastic Material Properties of the Myocardium and Cardiac Jelly in the Looping Chick Heart

Jiang Yao, Victor D. Varner, Lauren L. Brilli, Jonathan M. Young, Larry A. Taber, Renato Perucchio
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. February 2012, 134(2): 024502.
https://doi.org/10.1115/1.4005693
Published Online: February 15, 2012
View Article titled, Viscoelastic Material Properties of the Myocardium and Cardiac Jelly in the Looping Chick Heart
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Topics: Biological tissues, Computational methods, Constitutive equations, Density, Modeling, Myocardium, Stress, Viscoelastic materials, Relaxation (Physics), Displacement
Journal Articles

Simulation of Mechanical Environment in Active Lead Fixation: Effect of Fixation Helix Size

Xuefeng Zhao, Jonathan F. Wenk, Mike Burger, Yi Liu, Mithilesh K. Das, William Combs, Liang Ge, Julius M. Guccione, Ghassan S. Kassab
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. June 2011, 133(6): 061006.
https://doi.org/10.1115/1.4004288
Published Online: June 28, 2011
View Article titled, Simulation of Mechanical Environment in Active Lead Fixation: Effect of Fixation Helix Size
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Topics: Damage, Electrodes, Finite element analysis, Myocardium, Wire, Screws, Simulation, Failure, Pacemakers, Algorithms
Journal Articles

Simulation of LV Pacemaker Lead in Marginal Vein: Potential Risk Factors for Acute Dislodgement

Xuefeng Zhao, Mike Burger, Yi Liu, Mithilesh K. Das, William Combs, Jonathan F. Wenk, Julius M. Guccione, Ghassan S. Kassab
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2011, 133(3): 031006.
https://doi.org/10.1115/1.4003323
Published Online: February 7, 2011
View Article titled, Simulation of LV Pacemaker Lead in Marginal Vein: Potential Risk Factors for Acute Dislodgement
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Topics: Boundary-value problems, Constitutive equations, Finite element analysis, Myocardium, Pacemakers, Risk, Simulation