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Journal Articles

Artificial Neural Network-Aided Computational Approach for Mechanophenotyping of Biological Cells Using Atomic Force Microscopy

Yuvaraj Kamble, Abhishek Raj, Atul Thakur
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2023, 145(7): 071007.
Paper No: BIO-22-1218
https://doi.org/10.1115/1.4056916
Published Online: April 8, 2023
View Article titled, Artificial Neural Network-Aided Computational Approach for Mechanophenotyping of Biological Cells Using Atomic Force Microscopy
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Topics: Artificial neural networks, Atomic force microscopy, Simulation, Nanoindentation, Engineering simulation, Platelets, Finite element methods, Finite element model, Testing
Includes: Supplementary data
Journal Articles

Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning

Ali Behrangzade, Bruce R. Simon, William R. Wagner, Jonathan P. Vande Geest
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2023, 145(2): 021002.
Paper No: BIO-22-1025
https://doi.org/10.1115/1.4055563
Published Online: October 6, 2022
View Article titled, Optimizing the Porohyperelastic Response of a Layered Compliance Matched Vascular Graft to Promote Luminal Self-Cleaning
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Topics: Aorta, Fluids, Optimization, Permeability, Simulation, Flow (Dynamics), Thrombosis, Geometry, Finite element analysis, Platelets
Journal Articles

The Effects of Implantation Orientation of a Bileaflet Mechanical Heart Valve in an Anatomic Left Ventricle-Aorta Configuration

Hossein Asadi, Mohammadali Hedayat, Iman Borazjani
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2022, 144(10): 101008.
Paper No: BIO-21-1436
https://doi.org/10.1115/1.4054411
Published Online: May 12, 2022
View Article titled, The Effects of Implantation Orientation of a Bileaflet Mechanical Heart Valve in an Anatomic Left Ventricle-Aorta Configuration
Open the PDF for The Effects of Implantation Orientation of a Bileaflet Mechanical Heart Valve in an Anatomic Left Ventricle-Aorta Configuration in another window
Topics: Aorta, Cycles, Flow (Dynamics), Kinematics, Shear stress, Valves, Heart valve prostheses, Platelets, Simulation
Journal Articles

Ramifications of Vorticity on Aggregation and Activation of Platelets in Bi-Leaflet Mechanical Heart Valve: Fluid–Structure-Interaction Study

Meraj Ahmed, Nirmal Gupta, Rashmoni Jana, Malay K. Das, Kamal K. Kar
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. August 2022, 144(8): 081002.
Paper No: BIO-21-1102
https://doi.org/10.1115/1.4053665
Published Online: February 21, 2022
View Article titled, Ramifications of Vorticity on Aggregation and Activation of Platelets in Bi-Leaflet Mechanical Heart Valve: Fluid–Structure-Interaction Study
Open the PDF for Ramifications of Vorticity on Aggregation and Activation of Platelets in Bi-Leaflet Mechanical Heart Valve: Fluid–Structure-Interaction Study in another window
Topics: Flow (Dynamics), Fluids, Particulate matter, Platelets, Vorticity, Heart valve prostheses
Journal Articles

Models of Shear-Induced Platelet Activation and Numerical Implementation With Computational Fluid Dynamics Approaches

Dong Han, Jiafeng Zhang, Bartley P. Griffith, Zhongjun J. Wu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. April 2022, 144(4): 040801.
Paper No: BIO-21-1251
https://doi.org/10.1115/1.4052460
Published Online: November 5, 2021
View Article titled, Models of Shear-Induced Platelet Activation and Numerical Implementation With Computational Fluid Dynamics Approaches
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Topics: Platelets, Shear (Mechanics), Blood, Shear stress, Damage
Journal Articles

Lagrangian Trajectory Simulation of Platelets and Synchrotron Microtomography Augment Hemodynamic Analysis of Intracranial Aneurysms Treated With Embolic Coils

Venkat Keshav Chivukula, Laurel Marsh, Fanette Chassagne, Michael C. Barbour, Cory M. Kelly, Samuel Levy, Christian Geindreau, Sabine Rolland du Roscoat, Louis J. Kim, Michael R. Levitt, Alberto Aliseda
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2021, 143(7): 071002.
Paper No: BIO-20-1041
https://doi.org/10.1115/1.4050375
Published Online: April 1, 2021
View Article titled, Lagrangian Trajectory Simulation of Platelets and Synchrotron Microtomography Augment Hemodynamic Analysis of Intracranial Aneurysms Treated With Embolic Coils
Open the PDF for Lagrangian Trajectory Simulation of Platelets and Synchrotron Microtomography Augment Hemodynamic Analysis of Intracranial Aneurysms Treated With Embolic Coils in another window
Topics: Aneurysms, Hemodynamics, Platelets, Simulation, Computational fluid dynamics, Porous materials, Flow (Dynamics), Modeling
Includes: Supplementary data
Journal Articles

Mechanical Platelet Activation Potential in Abdominal Aortic Aneurysms

Kirk B. Hansen, Amirhossein Arzani, Shawn C. Shadden
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2015, 137(4): 041005.
Paper No: BIO-14-1355
https://doi.org/10.1115/1.4029580
Published Online: April 1, 2015
View Article titled, Mechanical Platelet Activation Potential in Abdominal Aortic Aneurysms
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Topics: Aneurysms, Platelets, Stress, Flow (Dynamics), Particulate matter, Physiology, Computational fluid dynamics
Journal Articles

Design of a Pulsatile Flow Facility to Evaluate Thrombogenic Potential of Implantable Cardiac Devices

Sivakkumar Arjunon, Pablo Hidalgo Ardana, Neelakantan Saikrishnan, Shalv Madhani, Brent Foster, Ari Glezer, Ajit P. Yoganathan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Design Innovation Paper
J Biomech Eng. April 2015, 137(4): 045001.
Paper No: BIO-14-1203
https://doi.org/10.1115/1.4029579
Published Online: April 1, 2015
View Article titled, Design of a Pulsatile Flow Facility to Evaluate Thrombogenic Potential of Implantable Cardiac Devices
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Topics: Blood, Cardiac cycle, Cardiovascular devices, Damage, Design, Flow (Dynamics), Pressure, Valves, Actuators, Platelets
Journal Articles

Blood Damage Through a Bileaflet Mechanical Heart Valve: A Quantitative Computational Study Using a Multiscale Suspension Flow Solver

B. Min Yun, Cyrus K. Aidun, Ajit P. Yoganathan
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2014, 136(10): 101009.
Paper No: BIO-13-1569
https://doi.org/10.1115/1.4028105
Published Online: August 12, 2014
View Article titled, Blood Damage Through a Bileaflet Mechanical Heart Valve: A Quantitative Computational Study Using a Multiscale Suspension Flow Solver
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Topics: Damage, Flow (Dynamics), Platelets, Simulation, Valves, Blood, Particulate matter, Modeling
Journal Articles

Thromboresistance Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD

Wei-Che Chiu, Gaurav Girdhar, Michalis Xenos, Yared Alemu, Jõao S. Soares, Shmuel Einav, Marvin Slepian, Danny Bluestein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2014, 136(2): 021014.
Paper No: BIO-13-1418
https://doi.org/10.1115/1.4026254
Published Online: February 5, 2014
View Article titled, Thromboresistance Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD
Open the PDF for Thromboresistance Comparison of the HeartMate II Ventricular Assist Device With the Device Thrombogenicity Emulation-Optimized HeartAssist 5 VAD in another window
Topics: Computer simulation, Flow (Dynamics), Impellers, Platelets, Thrombosis, Ventricular assist devices, Stress
Journal Articles

Hydrodynamic Interaction Between a Platelet and an Erythrocyte: Effect of Erythrocyte Deformability, Dynamics, and Wall Proximity

Koohyar Vahidkhah, Scott L. Diamond, Prosenjit Bagchi
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2013, 135(5): 051002.
Paper No: BIO-12-1280
https://doi.org/10.1115/1.4023522
Published Online: April 24, 2013
View Article titled, Hydrodynamic Interaction Between a Platelet and an Erythrocyte: Effect of Erythrocyte Deformability, Dynamics, and Wall Proximity
Open the PDF for Hydrodynamic Interaction Between a Platelet and an Erythrocyte: Effect of Erythrocyte Deformability, Dynamics, and Wall Proximity in another window
Topics: Platelets, Trajectories (Physics), Separation (Technology), Erythrocytes, Dynamics (Mechanics), Simulation
Journal Articles

In Vitro Evaluation of a Novel Hemodynamically Optimized Trileaflet Polymeric Prosthetic Heart Valve

Thomas E. Claiborne, Jawaad Sheriff, Maximilian Kuetting, Ulrich Steinseifer, Marvin J. Slepian, Danny Bluestein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. February 2013, 135(2): 021021.
Paper No: BIO-12-1474
https://doi.org/10.1115/1.4023235
Published Online: February 7, 2013
View Article titled, In Vitro Evaluation of a Novel Hemodynamically Optimized Trileaflet Polymeric Prosthetic Heart Valve
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Topics: Biological tissues, Design, Platelets, Valves, Finite element analysis, Engineering prototypes, Hydrodynamics, Polymers, Testing, Heart valve prostheses
Journal Articles

A Quantitative Comparison of Mechanical Blood Damage Parameters in Rotary Ventricular Assist Devices: Shear Stress, Exposure Time and Hemolysis Index

Katharine H. Fraser, Tao Zhang, M. Ertan Taskin, Bartley P. Griffith, Zhongjun J. Wu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. August 2012, 134(8): 081002.
https://doi.org/10.1115/1.4007092
Published Online: August 6, 2012
View Article titled, A Quantitative Comparison of Mechanical Blood Damage Parameters in Rotary Ventricular Assist Devices: Shear Stress, Exposure Time and Hemolysis Index
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Topics: Blood, Flow (Dynamics), Pressure, Shear stress, Damage, Ventricular assist devices, Scalars, Platelets, Computational fluid dynamics, Thrombosis
Journal Articles

Tortuosity Triggers Platelet Activation and Thrombus Formation in Microvessels

Jennifer K. W. Chesnutt, Hai-Chao Han
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. December 2011, 133(12): 121004.
https://doi.org/10.1115/1.4005478
Published Online: December 21, 2011
View Article titled, Tortuosity Triggers Platelet Activation and Thrombus Formation in Microvessels
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Topics: Adhesion, Fluids, Platelets, Simulation, Thrombosis, Vessels, Shear (Mechanics), Shear stress, Collisions (Physics), Flow (Dynamics)
Journal Articles

Two-Dimensional Simulation of Flow and Platelet Dynamics in the Hinge Region of a Mechanical Heart Valve

V. Govindarajan, H. S. Udaykumar, K. B. Chandran
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research Papers
J Biomech Eng. March 2009, 131(3): 031002.
https://doi.org/10.1115/1.3005158
Published Online: December 31, 2008
View Article titled, Two-Dimensional Simulation of Flow and Platelet Dynamics in the Hinge Region of a Mechanical Heart Valve
Open the PDF for Two-Dimensional Simulation of Flow and Platelet Dynamics in the Hinge Region of a Mechanical Heart Valve in another window
Topics: Flow (Dynamics), Geometry, Hinges, Platelets, Shear stress, Valves, Simulation, Ear, Heart valve prostheses, Shear (Mechanics)
Journal Articles

Comparison of the Hemodynamic and Thrombogenic Performance of Two Bileaflet Mechanical Heart Valves Using a CFD/FSI Model

Kris Dumont, Jan Vierendeels, Rado Kaminsky, Guido van Nooten, Pascal Verdonck, Danny Bluestein
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. August 2007, 129(4): 558–565.
https://doi.org/10.1115/1.2746378
Published Online: January 22, 2007
View Article titled, Comparison of the Hemodynamic and Thrombogenic Performance of Two Bileaflet Mechanical Heart Valves Using a CFD/FSI Model
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Topics: Computational fluid dynamics, Flow (Dynamics), Fluid structure interaction, Hemodynamics, Platelets, Shear stress, Valves, Stress, Heart valve prostheses, Hinges
Journal Articles

Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions

Anna M. Fallon, Nisha Shah, Ulla M. Marzec, James N. Warnock, Ajit P. Yoganathan, Stephen R. Hanson
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. February 2006, 128(1): 30–39.
https://doi.org/10.1115/1.2133768
Published Online: August 22, 2005
View Article titled, Flow and Thrombosis at Orifices Simulating Mechanical Heart Valve Leakage Regions
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Topics: Blood, Flow (Dynamics), Leakage, Orifices, Platelets, Thrombosis, Heart valve prostheses, Hinges, Shear stress
Journal Articles

Effect of Bone Mineral Content on the Tensile Properties of Cortical Bone: Experiments and Theory

S. P. Kotha, N. Guzelsu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. December 2003, 125(6): 785–793.
https://doi.org/10.1115/1.1631586
Published Online: January 9, 2004
View Article titled, Effect of Bone Mineral Content on the Tensile Properties of Cortical Bone: Experiments and Theory
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Topics: Bone, Minerals, Stress, Yield stress, Mechanical properties, Elastic moduli, Platelets, Shear (Mechanics), Tensile strength
Journal Articles

Numerical Simulation of Wall Shear Stress Conditions and Platelet Localization in Realistic End-to-Side Arterial Anastomoses

P. Worth Longest, Clement Kleinstreuer
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. October 2003, 125(5): 671–681.
https://doi.org/10.1115/1.1613298
Published Online: October 9, 2003
View Article titled, Numerical Simulation of Wall Shear Stress Conditions and Platelet Localization in Realistic End-to-Side Arterial Anastomoses
Open the PDF for Numerical Simulation of Wall Shear Stress Conditions and Platelet Localization in Realistic End-to-Side Arterial Anastomoses in another window
Topics: Flow (Dynamics), Hemodynamics, Particulate matter, Platelets, Shear (Mechanics), Shear stress, Simulation, Stress, Blood, Outflow
Journal Articles

On Assessing the Quality of Particle Tracking Through Computational Fluid Dynamic Models

Mauro Tambasco, David A. Steinman
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Papers
J Biomech Eng. April 2002, 124(2): 166–175.
https://doi.org/10.1115/1.1449489
Published Online: March 29, 2002
View Article titled, On Assessing the Quality of Particle Tracking Through Computational Fluid Dynamic Models
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Topics: Computational fluid dynamics, Flow (Dynamics), Fluids, Particulate matter, Finite element analysis, Platelets, Density, Computation, Bifurcation, Errors