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Journal Articles

A Spatial Interpolation Approach to Assign Magnetic Resonance Imaging-Derived Material Properties for Finite Element Models of Adeno-Associated Virus Infusion Into a Recurrent Brain Tumor

Reed Chen, Julian A. Rey, Ibrahim S. Tuna, David D. Tran, Malisa Sarntinoranont
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2024, 146(10): 101001.
Paper No: BIO-23-1134
https://doi.org/10.1115/1.4064966
Published Online: May 13, 2024
View Article titled, A Spatial Interpolation Approach to Assign Magnetic Resonance Imaging-Derived Material Properties for Finite Element Models of Adeno-Associated Virus Infusion Into a Recurrent Brain Tumor
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Topics: Biological tissues, Brain, Fluids, Hydraulic conductivity, Interpolation, Materials properties, Porosity, Tumors, Convection, Computer simulation
Includes: Supplementary data
Journal Articles

A Novel Port to Facilitate Magnetic Hyperthermia Therapy for Glioma

Benjamin Rodriguez, Peter Campbell, Joseph Borrello, Ian Odland, Tyree Williams, Eugene I. Hrabarchuk, Tirone Young, Anirudh Sharma, Alexander J. Schupper, Benjamin Rapoport, Robert Ivkov, Constantinos Hadjipanayis
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2024, 146(1): 011009.
Paper No: BIO-23-1207
https://doi.org/10.1115/1.4063556
Published Online: November 22, 2023
View Article titled, A Novel Port to Facilitate Magnetic Hyperthermia Therapy for Glioma
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Topics: Brain, Design, Iron, Nanoparticles, Patient treatment, Phantoms, Physiology, Tumors, Temperature, Biological tissues
Journal Articles

Non-Contact Irreversible Electroporation in the Esophagus With a Wet Electrode Approach

Mary Chase Sheehan, Scott Collins, Thomas Wimmer, Narendra Babu Gutta, Sebastian Monette, Jeremy C. Durack, Stephen B. Solomon, Govindarajan Srimathveeravalli
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2023, 145(9): 091004.
Paper No: BIO-22-1236
https://doi.org/10.1115/1.4062491
Published Online: May 22, 2023
View Article titled, Non-Contact Irreversible Electroporation in the Esophagus With a Wet Electrode Approach
Open the PDF for Non-Contact Irreversible Electroporation in the Esophagus With a Wet Electrode Approach in another window
Topics: Ablation (Vaporization technology), Biological tissues, Damage, Electrodes, Electroporation, Simulation, Tumors, Wire, Catheters, Electric fields
Includes: Supplementary data
Journal Articles

Hybrid Message-Passing Interface-Open Multiprocessing Accelerated Euler–Lagrange Simulations of Microbubble Enhanced HIFU for Tumor Ablation

Jingsen Ma, Xiaolong Deng, Chao-Tsung Hsiao, Georges L. Chahine
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. July 2023, 145(7): 071005.
Paper No: BIO-22-1301
https://doi.org/10.1115/1.4057050
Published Online: March 28, 2023
View Article titled, Hybrid Message-Passing Interface-Open Multiprocessing Accelerated Euler–Lagrange Simulations of Microbubble Enhanced HIFU for Tumor Ablation
Open the PDF for Hybrid Message-Passing Interface-Open Multiprocessing Accelerated Euler–Lagrange Simulations of Microbubble Enhanced HIFU for Tumor Ablation in another window
Topics: Bubbles, Simulation, Multiprocessing, Computation, Tumors, Ablation (Vaporization technology)
Journal Articles

Data-Driven Simulation of Fisher–Kolmogorov Tumor Growth Models Using Dynamic Mode Decomposition

Alex Viguerie, Malú Grave, Gabriel F. Barros, Guillermo Lorenzo, Alessandro Reali, Alvaro L. G. A. Coutinho
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. December 2022, 144(12): 121001.
Paper No: BIO-22-1059
https://doi.org/10.1115/1.4054925
Published Online: August 19, 2022
View Article titled, Data-Driven Simulation of Fisher–Kolmogorov Tumor Growth Models Using Dynamic Mode Decomposition
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Topics: Simulation, Tumors, Errors, Computer simulation, Cancer
Journal Articles

Lethal Electric Field Thresholds for Cerebral Cells With Irreversible Electroporation and H-FIRE Protocols: An In Vitro Three-Dimensional Cell Model Study

Ting Shu, Lujia Ding, Zheng Fang, Shuangquan Yu, Lingchao Chen, Michael A. J. Moser, Wenjun Zhang, Zhiyong Qin, Bing Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2022, 144(10): 101010.
Paper No: BIO-22-1024
https://doi.org/10.1115/1.4054381
Published Online: May 12, 2022
View Article titled, Lethal Electric Field Thresholds for Cerebral Cells With Irreversible Electroporation and H-FIRE Protocols: An In Vitro Three-Dimensional Cell Model Study
Open the PDF for Lethal Electric Field Thresholds for Cerebral Cells With Irreversible Electroporation and H-FIRE Protocols: An In Vitro Three-Dimensional Cell Model Study in another window
Topics: Ablation (Vaporization technology), Electric fields, Electrical conductivity, Electroporation, Fire, Temperature, Tumors, Brain
Journal Articles

Experimental and Numerical Investigation of Parameters Affecting High-Frequency Irreversible Electroporation for Prostate Cancer Ablation

Kenneth N. Aycock, Ram Anand Vadlamani, Edward J. Jacobs, IV, Khan Mohammad Imran, Scott S. Verbridge, Irving C. Allen, Navid Manuchehrabadi, Rafael V. Davalos
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061003.
Paper No: BIO-21-1372
https://doi.org/10.1115/1.4053595
Published Online: February 15, 2022
View Article titled, Experimental and Numerical Investigation of Parameters Affecting High-Frequency Irreversible Electroporation for Prostate Cancer Ablation
Open the PDF for Experimental and Numerical Investigation of Parameters Affecting High-Frequency Irreversible Electroporation for Prostate Cancer Ablation in another window
Topics: Ablation (Vaporization technology), Biological tissues, Cancer, Damage, Delays, Electric fields, Electroporation, Fire, Tumors, Performance
Includes: Supplementary data
Journal Articles

Confined Cell Migration and Asymmetric Hydraulic Environments to Evaluate the Metastatic Potential of Cancer Cells

Yago Juste-Lanas, Pedro Enrique Guerrero, Daniel Camacho-Gómez, Silvia Hervás-Raluy, Jose M. García-Aznar, María J. Gomez-Benito
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. July 2022, 144(7): 074502.
Paper No: BIO-21-1259
https://doi.org/10.1115/1.4053143
Published Online: February 15, 2022
View Article titled, Confined Cell Migration and Asymmetric Hydraulic Environments to Evaluate the Metastatic Potential of Cancer Cells
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Topics: Cancer, Microfluidics, Tumors
Includes: Supplementary data
Journal Articles

Using Parallel Coordinates in Optimization of Nano-Particle Drug Delivery

Timoleon Kipouros, Ibrahim Chamseddine, Michael Kokkolaras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. April 2022, 144(4): 044501.
Paper No: BIO-21-1174
https://doi.org/10.1115/1.4052578
Published Online: November 5, 2021
View Article titled, Using Parallel Coordinates in Optimization of Nano-Particle Drug Delivery
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Topics: Design, Drug delivery systems, Nanoparticles, Optimization, Tumors, Modeling, Drugs
Journal Articles

Electroporation-Based Therapy for Brain Tumors: A Review

Zheng Fang, Lingchao Chen, Michael A. J. Moser, Wenjun Zhang, Zhiyong Qin, Bing Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. October 2021, 143(10): 100802.
Paper No: BIO-21-1079
https://doi.org/10.1115/1.4051184
Published Online: June 17, 2021
View Article titled, Electroporation-Based Therapy for Brain Tumors: A Review
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Topics: Brain, Electroporation, Patient treatment, Tumors, Ablation (Vaporization technology), Electric fields, Blood, Membranes
Journal Articles

Thermal Simulations of Cancerous Breast Tumors and Cysts on a Realistic Female Torso

Francisco Javier González
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2021, 143(6): 061001.
Paper No: BIO-19-1463
https://doi.org/10.1115/1.4049957
Published Online: March 9, 2021
View Article titled, Thermal Simulations of Cancerous Breast Tumors and Cysts on a Realistic Female Torso
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Topics: Cancer, Simulation, Temperature, Thermography, Tumors, Biological tissues, Skin, Finite element analysis, Heat transfer, Infrared imaging
Journal Articles

Multiscale Computational Fluid Dynamics Modeling for Personalized Liver Cancer Radioembolization Dosimetry

Amirtahà Taebi, Catherine T. Vu, Emilie Roncali
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. January 2021, 143(1): 011002.
Paper No: BIO-19-1356
https://doi.org/10.1115/1.4047656
Published Online: September 30, 2020
View Article titled, Multiscale Computational Fluid Dynamics Modeling for Personalized Liver Cancer Radioembolization Dosimetry
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Topics: Computational fluid dynamics, Dosimetry, Flow (Dynamics), Liver, Tumors, Cancer, Blood flow
Includes: Supplementary data
Journal Articles

Treatment Planning Optimization in Irreversible Electroporation for Complete Ablation of Variously Sized Cervical Tumors: A Numerical Study

Lujia Ding, Michael Moser, Yigang Luo, Wenjun Zhang, Bing Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. January 2021, 143(1): 014503.
Paper No: BIO-20-1087
https://doi.org/10.1115/1.4047551
Published Online: September 29, 2020
View Article titled, Treatment Planning Optimization in Irreversible Electroporation for Complete Ablation of Variously Sized Cervical Tumors: A Numerical Study
Open the PDF for Treatment Planning Optimization in Irreversible Electroporation for Complete Ablation of Variously Sized Cervical Tumors: A Numerical Study in another window
Topics: Ablation (Vaporization technology), Electroporation, Tumors, Optimization, Electrodes, Modeling, Biological tissues
Journal Articles

A Dual Nanoparticle Delivery Strategy for Enhancing Drug Distribution in Cancerous Tissue

Ibrahim M. Chamseddine, Michael Kokkolaras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. December 2020, 142(12): 124501.
Paper No: BIO-19-1462
https://doi.org/10.1115/1.4047657
Published Online: September 8, 2020
View Article titled, A Dual Nanoparticle Delivery Strategy for Enhancing Drug Distribution in Cancerous Tissue
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Topics: Drugs, Nanoparticles, Tumors, Biological tissues, Optimization
Journal Articles

An Analytical Poroelastic Model of a Nonhomogeneous Medium Under Creep Compression for Ultrasound Poroelastography Applications—Part II

Md Tauhidul Islam, J. N. Reddy, Raffaella Righetti
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2019, 141(6): 060903.
Paper No: BIO-17-1554
https://doi.org/10.1115/1.4040604
Published Online: April 22, 2019
View Article titled, An Analytical Poroelastic Model of a Nonhomogeneous Medium Under Creep Compression for Ultrasound Poroelastography Applications—Part II
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Topics: Compression, Creep, Fluid pressure, Permeability, Poisson ratio, Fluids, Finite element model, Tumors, Biological tissues, Stress
Journal Articles

An Analytical Poroelastic Model of a Nonhomogeneous Medium Under Creep Compression for Ultrasound Poroelastography Applications—Part I

Md Tauhidul Islam, J. N. Reddy, Raffaella Righetti
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2019, 141(6): 060902.
Paper No: BIO-17-1553
https://doi.org/10.1115/1.4040603
Published Online: April 22, 2019
View Article titled, An Analytical Poroelastic Model of a Nonhomogeneous Medium Under Creep Compression for Ultrasound Poroelastography Applications—Part I
Open the PDF for An Analytical Poroelastic Model of a Nonhomogeneous Medium Under Creep Compression for Ultrasound Poroelastography Applications—Part I in another window
Topics: Fluid pressure, Tumors, Creep, Stress, Biological tissues, Compression, Ultrasound, Displacement, Fluids, Poisson ratio
Journal Articles

Design of a Novel Electrode of Radiofrequency Ablation for Large Tumors: In Vitro Validation and Evaluation

Zheng Fang, Micheal A. J. Moser, Edwin Zhang, Wenjun Zhang, Bing Zhang
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. March 2019, 141(3): 031007.
Paper No: BIO-18-1392
https://doi.org/10.1115/1.4042179
Published Online: January 18, 2019
View Article titled, Design of a Novel Electrode of Radiofrequency Ablation for Large Tumors: In Vitro Validation and Evaluation
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Topics: Ablation (Vaporization technology), Biological tissues, Electrodes, Liver, Radiofrequency ablation, Tumors, Computer simulation, Shapes
Journal Articles

Numerical Study of Transport of Anticancer Drugs in Heterogeneous Vasculature of Human Brain Tumors Using Dynamic Contrast Enhanced-Magnetic Resonance Imaging

Ajay Bhandari, Ankit Bansal, Anup Singh, Niraj Sinha
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. May 2018, 140(5): 051010.
Paper No: BIO-17-1366
https://doi.org/10.1115/1.4038746
Published Online: March 16, 2018
View Article titled, Numerical Study of Transport of Anticancer Drugs in Heterogeneous Vasculature of Human Brain Tumors Using Dynamic Contrast Enhanced-Magnetic Resonance Imaging
Open the PDF for Numerical Study of Transport of Anticancer Drugs in Heterogeneous Vasculature of Human Brain Tumors Using Dynamic Contrast Enhanced-Magnetic Resonance Imaging in another window
Topics: Drugs, Tumors
Journal Articles

Nanoparticle Optimization for Enhanced Targeted Anticancer Drug Delivery

Ibrahim M. Chamseddine, Michael Kokkolaras
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. April 2018, 140(4): 041002.
Paper No: BIO-17-1243
https://doi.org/10.1115/1.4038202
Published Online: January 19, 2018
View Article titled, Nanoparticle Optimization for Enhanced Targeted Anticancer Drug Delivery
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Topics: Drugs, Nanoparticles, Optimization, Tumors, Design, Vessels, Shapes
Journal Articles

Investigation of Biotransport in a Tumor With Uncertain Material Properties Using a Nonintrusive Spectral Uncertainty Quantification Method

Alen Alexanderian, Liang Zhu, Maher Salloum, Ronghui Ma, Meilin Yu
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. September 2017, 139(9): 091006.
Paper No: BIO-17-1044
https://doi.org/10.1115/1.4037102
Published Online: July 14, 2017
View Article titled, Investigation of Biotransport in a Tumor With Uncertain Material Properties Using a Nonintrusive Spectral Uncertainty Quantification Method
Open the PDF for Investigation of Biotransport in a Tumor With Uncertain Material Properties Using a Nonintrusive Spectral Uncertainty Quantification Method in another window
Topics: Materials properties, Permeability, Pressure, Tumors, Uncertainty, Uncertainty quantification, Porosity, Polynomials