... exposed to variable amounts of strain. Further work is needed to confirm the physiological load state of bone during growth to better elucidate the degree to which these variations are a function of the local mechanical environment. The purpose of the SMS condition was to test samples in the expected...

...Sriram Balasubramanian; Christian R. D'Andrea; Girish Viraraghavan; Patrick J. Cahill Finite element (FE) modeling of the spine has increasingly been applied in orthopedic precision-medicine approaches. Previously published FE models of the pediatric spine growth have made simplifications...

... error (RMSE) of 14.4%, 17.4%, and 15.2% for 28, 56, and 84 d.o. groups, respectively. Prediction errors were less than 13.5% for 28 and 84 d.o. groups but reached 57.1% for the 56 d.o. group. Relationships between bone physical and mechanical properties were found to change during the growth, similarly...

... We propose a novel thick-walled fluid–solid-growth (FSG) computational framework for modeling vascular disease evolution. The arterial wall is modeled as a thick-walled nonlinearly elastic cylindrical tube consisting of two layers corresponding to the media-intima and adventitia, where each layer...

...Nathan T. Balcom; Britta Berg-Johansen; Kristin J. Dills; Jennifer R. Van Donk; Gregory M. Williams; Albert C. Chen; Scott J. Hazelwood; Robert L. Sah; Stephen M. Klisch In vitro cultures with insulin-like growth factor-1 (IGF-1) and transforming growth factor-β1 (TGF-β1) have previously been shown...

...Jonathan M. Young; Jiang Yao; Ashok Ramasubramanian; Larry A. Taber; Renato Perucchio The analysis of the biomechanics of growth and remodeling in soft tissues requires the formulation of specialized pseudoelastic constitutive relations. The nonlinear finite element analysis package ABAQUS allows...

...Timothy P. Ficklin; Andrew Davol; Stephen M. Klisch Recently a cartilage growth finite element model (CGFEM) was developed to solve nonhomogeneous and time-dependent growth boundary-value problems ( Davol et al., 2008, “A Nonlinear Finite Element Model of Cartilage Growth,” Biomech. Model...