Abstract
Toxicological investigations were performed on an intracerebral hematoma, antemortem blood, and postmortem blood of an individual who was found unresponsive in his home. The hematoma was found to have ethanol at a concentration of 0.05% (w/v), and benzoylecgonine (a cocaine metabolite) was also confirmed at a concentration of 0.43 mg/L by specific analysis using gas chromatography/mass spectrometry (GC/MS). These results enabled the pathologist to record the cause of death as intracerebral hemorrhage due to acute cocaine intoxication.
Issue Section:
Research Papers
References
1.
Hirsch
CS
, Adelson
L
. Ethanol in sequestered hematomas
. Am J Clin Path
0002-9173 1973
;59
:429
–33
.2.
Freireich
AW
, Bidanset
JH
, Lukash
L
. Alcohol levels in intracranial blood clots
. J Forensic Sci
0022-1198 1975
;20
:83
–5
.3.
Eisele
JW
, Reay
DT
, Bonnell
HJ
. Ethanol in sequestered hematomas: Quantitative evaluation
. J Am Clin Pathol
0002-9173 1984
;81
:352
–5
.4.
Buchsbaum
RM
, Adelson
L
, Sunshine
I
. A comparison of postmortem ethanol levels obtained from blood and subdural specimens
. Forensic Sci Int
0379-0738 1989
;41
:237
–43
.5.
Moriya
F
, Hashimoto
Y
. Medicolegal implications of drugs and chemicals detected in intracranial hematomas
. J Forensic Sci
0022-1198 1998
;43
:980
–4
.6.
Kibayashi
K
, Mastri
AR
, Hirsch
CS
. Cocaine induced hemorrhage: analysis of predisposing factors and mechanisms causing hemorrhage strokes
. Hum Pathol
0046-8177 1995
;26
:659
–63
.7.
Nolte
KB
, Brass
LM
, Fletterick
CF
. Intracranial hemorrhage associated with cocaine abuse: a prospective autopsy study
. Neurology
0028-3878 1996
;46
: 1291–6.8.
Cassin
BJ
, Spitz
WU
. Concentration of alcohol in delayed subdural hematoma
. J Forensic Sci
0022-1198 1983
;28
:1013
–5
.9.
Anderson
WH
, Prouty
RW
. Postmortem redistribution of drugs
. In: Baselt
RC
, editor. Advances in analytical toxicology
, Vol., 2. Chicago
: Yearbook Medical
1989
;70
–102
.10.
Pounder
DJ
, Jones
GR
. Postmortem drug redistribution—a toxicological nightmare
. Forensic Sci Int
0379-0738 1990
;45
:253
–63
.
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