Abstract
We describe the application of histochemical demonstration of chromium in a case of fatal ingestion of potassium dichromate in a suicide attempt. Using 2-(8-quinolylazo)-4,5-di-p-tolylimidazole (QTI), we could demonstrate chromium in the erythrocyte of the victim, in situ. This finding provides a means of proving the hexavalent chromium ingestion.
Issue Section:
Technical Notes
References
1.
Ellenhorn
MJ
, Barceloux
DG
. Dichromate
. In: Ellenhorn
MJ
, Barceloux
DG
, editors. Medical toxicology diagnosis and treatment of human poisoning
. New York
: Elsevier
1988
;1020
–2
.2.
Michie
CA
, Hayhurst
M
, Knobel
GJ
, Stokol
JM
, Hensley
B
. Poisoning with a traditional remedy containing potassium dichromate
. Hum Exp Toxicol
0960-3271 1991
;10
:129
–31
.3.
Barceloux
DG
. Chromium
. J Toxicol Clin Toxicol
0731-3810 1999
;37
:173
–94
.4.
Pascale
LR
, Waldstein
S
, Engbring
G
, Dubin
A
. Chromium intoxication with special reference to hepatic injury
. JAMA
0098-7484 1952
;149
:1385
–9
.5.
Kaufman
DB
, DiNicola
W
, McIntosh
R
. Acute potassium dichromate poisoning treated by peritoneal dialysis
. Amer J Dis Child
1970
;119
:374
–6
.6.
Sumi
Y
, Itoh
MT
, Yoshida
M
, Suzuki
T
. Histochemical staining of chromium with 2-(8-quinolylazo)-4,5-di-p-tolylimidazole
. Eur J Histochem
0391-7258 1998
;42
:271
–6
.7.
Tanaka
T
, Nose
T
, Hayashi
Y
, Sugiyama
K
, Funakawa
K
, Ishizawa
M
. Concentration of chromium in biological materials (blood, serum, urine and scarp hair) from the chromium mine workers
. Medicine and Biology
0302-2137 1980
;101
:277
–81
.8.
Kinoshita
H
, Koizumi
M
, Ijiri
I
, Ameno
S
, Seki
K
, Kumihashi
M
, et al. A fatal case due to potassium dichromate ingestion
. Jpn J Toxicol
2000
;13
:407
–9
.9.
Sumi
Y
, Muraki
T
, Suzuki
T
. The choice of a masking agent in the histochemical staining of metals
. Histochem J
0018-2214 1983
;15
:231
–8
.10.
Sumi
Y
, Muraki
T
, Suzuki
T
. Histochemical staining of cadmium with benzothiazolylazonaphthol derivatives
. Histochemistry
0301-5564 1982
;73
:481
–6
.11.
Gray
SJ
, Sterling
K
. The tagging of red cells and plasma proteins with radioactive chromium
. J Clin Invest
0021-9738 1950
;29
:1604
–13
.12.
Pearson
HA
, Vertrees
KM
. Site of binding of chromium 51 to haemoglobin
. Nature
0028-0836 1961
;189
:1019
–20
.
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