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Keywords: degraded DNA
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Journal Articles
Journal Articles
Publisher: ASTM International
Article Type: Research-Article
J. Forensic Sci.. January 2005, 50(1): JFS2004216–11.
Published Online: January 1, 2005
...MD Coble, Ph.D.; JM Butler, Ph.D. A number of studies have demonstrated that successful analysis of degraded DNA specimens from mass disasters or forensic evidence improves with smaller sized polymerase chain reaction (PCR) products. We have scanned the literature for new STR loci, unlinked from...
Journal Articles
Publisher: ASTM International
Article Type: Research-Article
J. Forensic Sci.. July 2004, 49(4): 1–8.
Published Online: July 1, 2004
... with redesigned primer sequences called "Miniplexes" to produce smaller amplicons. To assess the effectiveness of these kits, we have tested these primer sets with enzymatically degraded DNA and compared the amplifications to a commercial kit. We also conducted sensitivity and peak balance studies of three...
Journal Articles
Publisher: ASTM International
Article Type: Research-Article
J. Forensic Sci.. September 2003, 48(5): 1–11.
Published Online: September 1, 2003
... the examination and analysis of degraded DNA evidence by improving amplification efficiency. This "miniSTR" approach will permit current forensic practitioners to use STR markers and instrumentation already present in their laboratories and to generate genotyping data that is directly comparable to reference...
Journal Articles
Publisher: ASTM International
Article Type: Technical Notes
J. Forensic Sci.. May 2001, 46(3): 677–680.
Published Online: May 1, 2001
... dot. Since the S dot acts as a minimum dot intensity control to determine positive alleles on the PM loci, it is necessary to apply another control system. To achieve positive PM typing from a degraded DNA sample that is inferred to be derived from a single donor, a standard has been adopted wherein...