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Ian A. Sigal
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Journal Articles

Stretch-Induced Uncrimping of Equatorial Sclera Collagen Bundles

Ning-Jiun Jan, Po-Yi Lee, Jacob Wallace, Michael Iasella, Alexandra Gogola, Bingrui Wang, Ian A. Sigal
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. May 2023, 145(5): 054503.
Paper No: BIO-22-1243
https://doi.org/10.1115/1.4056354
Published Online: December 21, 2022
View Articletitled, Stretch-Induced Uncrimping of Equatorial Sclera Collagen Bundles
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Topics: Biological tissues, Clamps (Tools), Failure, Fibers, Biomechanics, Imaging, Polarization (Light)
Journal Articles

A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network

Po-Yi Lee, Yi Hua, Bryn L. Brazile, Bin Yang, Lin Wang, Ian A. Sigal
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. June 2022, 144(6): 061006.
Paper No: BIO-21-1403
https://doi.org/10.1115/1.4054056
Published Online: March 24, 2022
View Articletitled, A Workflow for Three-Dimensional Reconstruction and Quantification of the Monkey Optic Nerve Head Vascular Network
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Topics: Vessels, Workflow, Imaging, Biological tissues
Proceedings Papers

Large Scale Voxel-Based Finite Element Modeling of Normal and Early Glaucomatous Monkey Lamina Cribrosa

Sanjay Kodiyalam, Michael D. Roberts, Ian A. Sigal, Richard T. Hart, Claude F. Burgoyne, J. Crawford Downs
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 553-554, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192984
https://doi.org/10.1115/SBC2008-192984
View Paper titled, Large Scale Voxel-Based Finite Element Modeling of Normal and Early Glaucomatous Monkey Lamina Cribrosa
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Topics: Biological tissues, Canals, Damage, Diseases, Finite element analysis, Modeling, Poles (Building), Pressure, Stress
Proceedings Papers

Mechanics of Individual-Specific Corneoscleral Shell Models

Richard E. Norman, Ian A. Sigal, Sophie M. K. Rausch, Inka Tertinegg, Armin Eilaghi, Sharon Portnoy, John G. Sled, John G. Flanagan, C. Ross Ethier
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 775-776, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-192576
https://doi.org/10.1115/SBC2008-192576
View Paper titled, Mechanics of Individual-Specific Corneoscleral Shell Models
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Topics: Diseases, Fibers, Shells, Stress
Proceedings Papers

Using Mesh Morphing to Study the Influence of Geometry on Biomechanics: An Example in Ocular Biomechanics

Ian A. Sigal, Hongli Yang, Michael D. Roberts, J. Crawford Downs
Proc. ASME. SBC2008, ASME 2008 Summer Bioengineering Conference, Parts A and B, 619-620, June 25–29, 2008
Publisher: American Society of Mechanical Engineers
Paper No: SBC2008-193069
https://doi.org/10.1115/SBC2008-193069
View Paper titled, Using Mesh Morphing to Study the Influence of Geometry on Biomechanics: An Example in Ocular Biomechanics
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Topics: Biomechanics, Geometry, Finite element analysis, Finite element model, Shapes
Proceedings Papers

Interactions Between Factors Influencing Optic Nerve Head Biomechanics

Ian A. Sigal, John G. Flanagan, C. Ross Ethier
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 891-892, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176096
https://doi.org/10.1115/SBC2007-176096
View Paper titled, Interactions Between Factors Influencing Optic Nerve Head Biomechanics
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Topics: Biomechanics, Finite element methods, Damage, Diseases, Pressure, Risk
Proceedings Papers

The Effect of Nonlinear Scleral Properties on Optic Nerve Head Biomechanics

Armin Eilaghi, Ian A. Sigal, Christian G. Olesen, Inka Tertinegg, John G. Flanagan, G. Wayne Brodland, C. Ross Ethier
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 901-902, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176251
https://doi.org/10.1115/SBC2007-176251
View Paper titled, The Effect of Nonlinear Scleral Properties on Optic Nerve Head Biomechanics
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Topics: Biomechanics, Damage, Diseases, Pressure
Proceedings Papers

The Influence of Material Properties and Geometry on Optic Nerve Head Biomechanics

Hongli Yang, Ian A. Sigal, Michael D. Roberts, Claude F. Burgoyne, J. Crawford Downs
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 711-712, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206513
https://doi.org/10.1115/SBC2009-206513
View Paper titled, The Influence of Material Properties and Geometry on Optic Nerve Head Biomechanics
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Topics: Biomechanics, Geometry, Materials properties, Diseases, Arches, Biological tissues, Canals, Pressure, Stress
Proceedings Papers

Biomechanics of the Posterior Pole During the Remodeling Progression From Normal to Early Experimental Glaucoma

Ian A. Sigal, Hongli Yang, Michael D. Roberts, Claude F. Burgoyne, J. Crawford Downs
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 363-364, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206518
https://doi.org/10.1115/SBC2009-206518
View Paper titled, Biomechanics of the Posterior Pole During the Remodeling Progression From Normal to Early Experimental Glaucoma
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Topics: Biological tissues, Biomechanics, Brain, Damage, Poles (Building), Pressure, Risk
Proceedings Papers

Finite Element Modeling of the Connective Tissues of the Optic Nerve Head in Bilaterally Normal Monkeys

Michael D. Roberts, Ian A. Sigal, Yi Liang, Claude F. Burgoyne, J. Crawford Downs
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 365-366, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206522
https://doi.org/10.1115/SBC2009-206522
View Paper titled, Finite Element Modeling of the Connective Tissues of the Optic Nerve Head in Bilaterally Normal Monkeys
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Topics: Biological tissues, Diseases, Finite element analysis, Fuels, Modeling, Patient treatment, Pressure
Proceedings Papers

Eye-Specific Measurement of the Microstructure and Biomechanics of the Human Lamina Cribrosa

Ian A. Sigal, Jonathan L. Grimm, Ning-Jiun Jan, Korey Reid, Donald J. Brown
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1173-1174, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80451
https://doi.org/10.1115/SBC2012-80451
View Paper titled, Eye-Specific Measurement of the Microstructure and Biomechanics of the Human Lamina Cribrosa
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Topics: Biomechanics, Brain, Damage, Pressure, Risk, Shrinkage (Materials), Warping
Proceedings Papers

Stochastic Modeling to Identify the Normal Response of an Optic Nerve Head to Small Increases in Intraocular Pressure

Ian A. Sigal, Jonathan L. Grimm
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 1297-1298, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53303
https://doi.org/10.1115/SBC2011-53303
View Paper titled, Stochastic Modeling to Identify the Normal Response of an Optic Nerve Head to Small Increases in Intraocular Pressure
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Topics: Modeling, Pressure, Biomechanics, Diseases, Risk
Proceedings Papers

Microstructure Motivated Growth and Remodeling of the Lamina Cribrosa in Early Glaucoma

Rafael Grytz, Ian A. Sigal, Jeffrey W. Ruberti, J. Crawford Downs
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 601-602, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53780
https://doi.org/10.1115/SBC2011-53780
View Paper titled, Microstructure Motivated Growth and Remodeling of the Lamina Cribrosa in Early Glaucoma
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Topics: Biological tissues, Diseases, Poles (Building), Pressure, Risk