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Journal Articles

Simulated Effects of Acute Left Ventricular Myocardial Infarction on Mitral Regurgitation in an Ovine Model

Hao Liu, Michael S. Sacks, Natalie T. Simonian, Joseph H. Gorman, III, Robert C. Gorman
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. October 2024, 146(10): 101009.
Paper No: BIO-23-1153
https://doi.org/10.1115/1.4065376
Published Online: June 6, 2024
View Article titled, Simulated Effects of Acute Left Ventricular Myocardial Infarction on Mitral Regurgitation in an Ovine Model
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Topics: Valves, Simulation, Deformation, Geometry, Myocardium
Journal Articles

A Computational Pipeline for Patient-Specific Prediction of the Postoperative Mitral Valve Functional State

Hao Liu, Natalie T. Simonian, Alison M. Pouch, Paul A. Iaizzo, Joseph H. Gorman, III, Robert C. Gorman, Michael S. Sacks
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Research-Article
J Biomech Eng. November 2023, 145(11): 111002.
Paper No: BIO-23-1060
https://doi.org/10.1115/1.4062849
Published Online: August 2, 2023
View Article titled, A Computational Pipeline for Patient-Specific Prediction of the Postoperative Mitral Valve Functional State
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Topics: Geometry, Valves, Simulation, Pipelines, Maintenance, Calibration, Imaging
Journal Articles

On the Simulation of Mitral Valve Function in Health, Disease, and Treatment

Michael S. Sacks, Andrew Drach, Chung-Hao Lee, Amir H. Khalighi, Bruno V. Rego, Will Zhang, Salma Ayoub, Ajit P. Yoganathan, Robert C. Gorman, Joseph H., Gorman, III
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Review Articles
J Biomech Eng. July 2019, 141(7): 070804.
Paper No: BIO-18-1408
https://doi.org/10.1115/1.4043552
Published Online: June 3, 2019
View Article titled, On the Simulation of Mitral Valve Function in Health, Disease, and Treatment
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Topics: Biological tissues, Geometry, Simulation, Valves, Modeling, Fibers, Maintenance, Surgery, Stress
Journal Articles

Computational Investigation of Transmural Differences in Left Ventricular Contractility

Hua Wang, Xiaoyan Zhang, Shauna M. Dorsey, Jeremy R. McGarvey, Kenneth S. Campbell, Jason A. Burdick, Joseph H. Gorman, III, James J. Pilla, Robert C. Gorman, Jonathan F. Wenk
Journal: Journal of Biomechanical Engineering
Publisher: ASME
Article Type: Technical Briefs
J Biomech Eng. November 2016, 138(11): 114501.
Paper No: BIO-16-1197
https://doi.org/10.1115/1.4034558
Published Online: October 21, 2016
View Article titled, Computational Investigation of Transmural Differences in Left Ventricular Contractility
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Topics: Deformation, Finite element model, Magnetic resonance imaging, Optimization, Tension, Pressure, Pumps, Fibers, Diseases, Finite element analysis
Proceedings Papers

In Vivo Dynamic Strains of the Mitral Valve Annulus

Brett Zubiate, Michael Sacks, Robert C. Gorman, Joseph H. Gorman
Proc. ASME. SBC2007, ASME 2007 Summer Bioengineering Conference, 247-248, June 20–24, 2007
Publisher: American Society of Mechanical Engineers
Paper No: SBC2007-176752
https://doi.org/10.1115/SBC2007-176752
View Paper titled, In Vivo Dynamic Strains of the Mitral Valve Annulus
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Topics: Annulus, Valves, Deformation, Cardiac cycle, Resolution (Optics), Biological tissues, Boundary-value problems, Crystals, Geometry, Shapes
Proceedings Papers

A Novel Micro-CT Based Anatomically Accurate Finite Element Model for Simulation-Aided Assessment of Mitral Valve Repairs

Chung-Hao Lee, Robert C. Gorman, Joseph H. Gorman, III, Rouzbeh Aimini, Michael S. Sacks
Proc. ASME. FMD2013, ASME 2013 Conference on Frontiers in Medical Devices: Applications of Computer Modeling and Simulation, V001T10A035, September 11–13, 2013
Publisher: American Society of Mechanical Engineers
Paper No: FMD2013-16136
https://doi.org/10.1115/FMD2013-16136
View Paper titled, A Novel Micro-CT Based Anatomically Accurate Finite Element Model for Simulation-Aided Assessment of Mitral Valve Repairs
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Topics: Finite element model, Maintenance, Simulation, Valves, Biological tissues, Constitutive equations, Deformation, Durability, Fibers, Finite element analysis
Proceedings Papers

A High Fidelity, Micro-Structural and Anatomically Accurate 3D Finite Element Model for Functioning Heart Mitral Valve

Chung-Hao Lee, Pim J. A. Oomen, Jean Pierre Rabbah, Neela Saikrishnan, Ajit Yoganathan, Robert C. Gorman, Joseph H. Gorman, III, Michael S. Sacks, Rouzebeh Amini
Proc. ASME. SBC2013, Volume 1B: Extremity; Fluid Mechanics; Gait; Growth, Remodeling, and Repair; Heart Valves; Injury Biomechanics; Mechanotransduction and Sub-Cellular Biophysics; MultiScale Biotransport; Muscle, Tendon and Ligament; Musculoskeletal Devices; Multiscale Mechanics; Thermal Medicine; Ocular Biomechanics; Pediatric Hemodynamics; Pericellular Phenomena; Tissue Mechanics; Biotransport Design and Devices; Spine; Stent Device Hemodynamics; Vascular Solid Mechanics; Student Paper and Design Competitions, V01BT30A003, June 26–29, 2013
Publisher: American Society of Mechanical Engineers
Paper No: SBC2013-14315
https://doi.org/10.1115/SBC2013-14315
View Paper titled, A High Fidelity, Micro-Structural and Anatomically Accurate 3D Finite Element Model for Functioning Heart Mitral Valve
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Topics: Finite element model, Valves, Maintenance, Biological tissues, Stress, Constitutive equations, Damage, Design, Durability, Failure
Proceedings Papers

Tunable Hyaluronic Acid Hydrogels to Alter and Understand Left Ventricular Remodeling

Elena Tous, Jamie L. Ifkovits, Shauna M. Dorsey, Spencer E. Szczesny, Kevin J. Koomalsingh, Takashi Shuto, Toru Soeda, Joseph H. Gorman, III, Dawn M. Elliott, Robert C. Gorman, Jason A. Burdick
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1013-1014, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80284
https://doi.org/10.1115/SBC2012-80284
View Paper titled, Tunable Hyaluronic Acid Hydrogels to Alter and Understand Left Ventricular Remodeling
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Topics: Biological tissues, Coronary arteries, Diseases, Heart failure, Hydrogels, Myocardium, Patient treatment, Stress
Proceedings Papers

Synchronous Dynamic In-Vivo Deformation of the Mitral Valve Leaflet and Annulus

Chad E. Eckert, Joseph H. Gorman, III, Robert C. Gorman, Michael S. Sacks
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 77-78, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206712
https://doi.org/10.1115/SBC2009-206712
View Paper titled, Synchronous Dynamic In-Vivo Deformation of the Mitral Valve Leaflet and Annulus
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Topics: Annulus, Deformation, Valves, Blood, Boundary-value problems, Finite element analysis, Kinematics, Mechanical properties, Modeling, Pressure
Proceedings Papers

Injectable Hyaluronic Acid Hydrogels to Attenuate Post-Infarction Left Ventricular Remodeling

Jamie L. Ifkovits, Elena Tous, Masato Morita, Joseph H. Gorman, III, Robert C. Gorman, Jason A. Burdick
Proc. ASME. SBC2009, ASME 2009 Summer Bioengineering Conference, Parts A and B, 157-158, June 17–21, 2009
Publisher: American Society of Mechanical Engineers
Paper No: SBC2009-206461
https://doi.org/10.1115/SBC2009-206461
View Paper titled, Injectable Hyaluronic Acid Hydrogels to Attenuate Post-Infarction Left Ventricular Remodeling
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Topics: Finite element model, Hydrogels, Myocardium, Simulation, Stress
Proceedings Papers

Integration of Microstructural Architecture of the Mitral Valve Into an Anatomically Accurate Finite Element Mesh

Rouzbeh Amini, Inge van Loosdregt, Kevin Koomalsingh, Robert C. Gorman, Joseph H. Gorman, III, Michael S. Sacks
Proc. ASME. SBC2012, ASME 2012 Summer Bioengineering Conference, Parts A and B, 1045-1046, June 20–23, 2012
Publisher: American Society of Mechanical Engineers
Paper No: SBC2012-80752
https://doi.org/10.1115/SBC2012-80752
View Paper titled, Integration of Microstructural Architecture of the Mitral Valve Into an Anatomically Accurate Finite Element Mesh
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Topics: Finite element analysis, Valves, Stress, Durability, Geometry, Maintenance, Fibers, Bearings, Biological tissues, Constitutive equations
Proceedings Papers

Functional Dynamic In-Vivo Stresses of the Mitral Valve Anterior Leaflet

Rouzbeh Amini, Chad E. Eckert, Christopher A. Carruthers, Kevin Koomalsingh, Mashito Minakawa, Robert C. Gorman, Joseph H. Gorman, Michael S. Sacks
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 257-258, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53925
https://doi.org/10.1115/SBC2011-53925
View Paper titled, Functional Dynamic In-Vivo Stresses of the Mitral Valve Anterior Leaflet
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Topics: Stress, Valves, Biological tissues, Constitutive equations, Damage, Durability, Failure, Failure mechanisms, Maintenance, Surgery
Proceedings Papers

Localized Cooling Device for Myocardial Tissue Salvage

Jennifer E. Akers, Denise R. Merrill, Todd J. Nilsen, Kevin J. Koomalsingh, Masahito Minakawa, Takashi Shuto, Joseph H. Gorman, III, Robert C. Gorman, Matthew J. Gillespie, Thomas L. Merrill
Proc. ASME. SBC2011, ASME 2011 Summer Bioengineering Conference, Parts A and B, 171-172, June 22–25, 2011
Publisher: American Society of Mechanical Engineers
Paper No: SBC2011-53155
https://doi.org/10.1115/SBC2011-53155
View Paper titled, Localized Cooling Device for Myocardial Tissue Salvage
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Topics: Biological tissues, Blood flow, Cascades (Fluid dynamics), Cooling, Flow (Dynamics), Patient treatment, Salvage (Wastes), Wounds
Proceedings Papers

Closed-Loop Lumped Parameter Cardiovascular Model of Infarct Border Zone Pacing

James J. Pilla, Kevin Koomalsingh, Robert C. Gorman
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 641-642, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19440
https://doi.org/10.1115/SBC2010-19440
View Paper titled, Closed-Loop Lumped Parameter Cardiovascular Model of Infarct Border Zone Pacing
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Topics: Cardiovascular system, Myocardium, Heart failure, Hemodynamics
Proceedings Papers

A Novel Approach to Quantify Alterations in Ventricular Principal Strain Vectors Secondary to Ischemic Injury

Chun Xu, Kevin Koomalsingh, Gamaliel Isaac, Robert C. Gorman, Joseph H. Gorman, III, Lawrence Dougherty, James J. Pilla
Proc. ASME. SBC2010, ASME 2010 Summer Bioengineering Conference, Parts A and B, 95-96, June 16–19, 2010
Publisher: American Society of Mechanical Engineers
Paper No: SBC2010-19068
https://doi.org/10.1115/SBC2010-19068
View Paper titled, A Novel Approach to Quantify Alterations in Ventricular Principal Strain Vectors Secondary to Ischemic Injury
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Topics: Computers, Diseases, Visualization, Wounds